The Giorgio Foundation in the News
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Insights into the pathogenesis of NF1-associated neoplasms
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Translating current basic research into future therapies for Neurofibromatosis Type 1
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Dr Lu Le’s Lab Develops New Method to Remove Dermal Tumors
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Mutation and loss underlies sporadic dermal neurofibroma pathogenesis and growth
Defining the research landscape for dermal neruofibromas
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Roles of nerve microenvironment for neurofibroma development.
Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins
Updated nomenclature for the human and mouse Neurofibromatosis
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Neurofibromin (NF1) genetic variant structure-function analyses using a full-length mouse cDNA
Tumorigenesis in neurofibromatosis type 1: role in the microenvironment
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Cutaneous neurofibromas in the genomics era: current understanding and open questions
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Cancer discovery spatiotemporal loss of NF1 in Schwann cell lineage leads to different types of cutaneous neurofibroma susceptible to modification
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Giorgio Foundation/University of Pittsburgh Establish Chair to Advance NF1 Research
The Giorgio Foundation and the University of Pittsburgh announce the establishment of The Giorgio Foundation Endowed Chair in the School of Medicine's Department of Neurosurgery with a total commitment of $2 million. This gift will support groundbreaking research in neurological conditions, with a specific focus on neurofibromatosis type 1 (NF1) in both pediatric and adult patients.
"The chair's primary focus will remain on advancing research and treatment for this condition until we cure neurofibromatosis type 1," said Anantha Shekhar, senior vice chancellor for the health sciences and John and Gertrude Petersen Dean of the School of Medicine at Pitt.
A major development in progress towards slowing or stopping the development of dermal neurofibromas has been discovered by Dr. Lu Le and his team at University of Texas Southwestern.
Dr Lu Le published in “Cancer Discovery”
Promising new research about origin of NF tumors funded by The Giorgio Foundation
More NF research from UT-Southwestern was published in this 2020 edition of Neuro-Oncology Advances. There are new insights into the origin cells for NF-related tumors. Pinpointing this cell is very important in developing targeted therapy.
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